› 8v2s

Electron Microscopy
2.72Å resolution

CHMP1B/IST1 dsDNA bound copolymer

Released:
DOI: 10.2210/pdb8v2s/pdb
PDB entry 8v2s coloured by chain, front view.
PDB entry 8v2s coloured by chain, side view.
PDB entry 8v2s coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Talledge N, Laughlin TG, Alian A
Related structures: EMD-42932

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero 192-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-281632 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Charged multivesicular body protein 1b Chain: A
Molecule details ›
Chain: A
Length: 199 amino acids
Theoretical weight: 22.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q7LBR1 (Residues: 1-199; Coverage: 100%)
Gene names: C18orf2, CHMP1B
Sequence domains: Snf7
IST1 homolog Chain: B
Molecule details ›
Chain: B
Length: 364 amino acids
Theoretical weight: 39.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P53990 (Residues: 1-364; Coverage: 100%)
Gene names: IST1, KIAA0174
Sequence domains: Regulator of Vps4 activity in the MVB pathway

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 2.72Å
Relevant EMDB volumes: EMD-42932
Expression system: Escherichia coli BL21(DE3)

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