Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-270860 (preferred)
Entry contents:
2 distinct polypeptide molecules
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (4 distinct):
DNA polymerase subunit gamma-1
Molecule details ›
Chain: A
Length: 1229 amino acids
Theoretical weight: 138.72 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
Sequence domains: DNA mitochondrial polymerase exonuclease domain
Length: 1229 amino acids
Theoretical weight: 138.72 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
- Canonical:
P54098 (Residues: 26-1239; Coverage: 98%)
Sequence domains: DNA mitochondrial polymerase exonuclease domain
DNA polymerase subunit gamma-2
Molecule details ›
Chains: B, C
Length: 474 amino acids
Theoretical weight: 53.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Anticodon binding domain
Length: 474 amino acids
Theoretical weight: 53.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q9UHN1 (Residues: 26-485; Coverage: 95%)
Sequence domains: Anticodon binding domain
