› 8v6p

X-ray diffraction
1.74Å resolution

Proteus vulgaris tryptophan indole-lyase complexed with 7-aza-L-tryptophan

Released:
DOI: 10.2210/pdb8v6p/pdb
PDB entry 8v6p coloured by chain, front view.
PDB entry 8v6p coloured by chain, side view.
PDB entry 8v6p coloured by chain, top view.
Source organism: Proteus vulgaris
Entry author: Phillips RS

Function and Biology Details

Reaction catalysed: 
(1a) L-tryptophan = indole + 2-aminoprop-2-enoate
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151290 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tryptophanase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 467 amino acids
Theoretical weight: 52.56 KDa
Source organism: Proteus vulgaris
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P28796 (Residues: 1-467; Coverage: 100%)
Gene name: tnaA
Sequence domains: Beta-eliminating lyase

Ligands and Environments

4 bound ligands:
Ligand K 2 x K
Ligand A1ACN 2 x A1ACN
Ligand DMS 1 x DMS
Ligand A1ABZ 2 x A1ABZ
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21212
Unit cell:
a: 151.635Å b: 211.34Å c: 60.956Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.187 0.185 0.228
Expression system: Escherichia coli BL21(DE3)

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