› 8v6q

X-ray diffraction
2.62Å resolution

Crystal structure of EcThsA in ligand-free state

Released:
DOI: 10.2210/pdb8v6q/pdb
PDB entry 8v6q coloured by chain, front view.
PDB entry 8v6q coloured by chain, side view.
PDB entry 8v6q coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
Structural characterization of macro domain-containing Thoeris antiphage defense systems.
Shi Y, Masic V, Mosaiab T, Rajaratman P, Hartley-Tassell L, Sorbello M, Goulart CC, Vasquez E, Mishra BP, Holt S, Gu W, Kobe B, Ve T
OpenAccess logo Sci Adv 10 eadn3310 (2024)
PMID: 38924412

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-268845 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thoeris protein ThsA Macro domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 241 amino acids
Theoretical weight: 27.81 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A178STJ6 (Residues: 62-278; Coverage: 78%)
Gene names: FPI65_12015, PWL68_000628
Sequence domains: Thoeris protein ThsA, Macro domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Unit cell:
a: 40.036Å b: 93.541Å c: 140.541Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.243 0.241 0.268
Expression system: Escherichia coli

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