› 8v9h

X-ray diffraction
1.5Å resolution

Function and Biology Details

Reaction catalysed: 
A beta-lactam + H(2)O = a substituted beta-amino acid
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-242666 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-lactamase GES-5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 287 amino acids
Theoretical weight: 31.22 KDa
Source organism: Klebsiella pneumoniae
Expression system: Escherichia coli
UniProt:
  • Canonical: Q09HD0 (Residues: 1-287; Coverage: 100%)
Gene names: blaGES-5, pGES-GZ_027
Sequence domains:

Ligands and Environments

5 bound ligands:
Ligand Y33 2 x Y33
Ligand EDO 4 x EDO
Ligand IOD 3 x IOD
Ligand CA 1 x CA
Ligand CL 7 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P212121
Unit cell:
a: 76.727Å b: 80.381Å c: 87.706Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.161 0.16 0.192
Expression system: Escherichia coli

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