8vbb

Electron Microscopy
3.97Å resolution

The secreted adhesin EtpA of Enterotoxigenic Escherichia coli in complex with the mouse mAb 1G05

Released:
Entry authors: Berndsen ZT, Ward AB
Related structures: EMD-43119

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-278784 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 1564 amino acids
Theoretical weight: 157.46 KDa
Source organism: Escherichia coli ETEC H10407
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q29XT7 (Residues: 1-1534; Coverage: 87%)
Gene name: etpA
Sequence domains:
mouse mAb 1G05 Heavy Chain Chain: H
Molecule details ›
Chain: H
Length: 467 amino acids
Theoretical weight: 51.43 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
mouse mAb 1G05 Light Chain Chain: L
Molecule details ›
Chain: L
Length: 233 amino acids
Theoretical weight: 25.41 KDa
Source organism: Mus musculus
Expression system: Homo sapiens

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.97Å
Relevant EMDB volumes: EMD-43119
Expression systems:
  • Escherichia coli BL21(DE3)
  • Homo sapiens