› 8vcr

Electron Microscopy
3Å resolution

SARS-CoV-2 Spike S2 bound to Fab 54043-5

Released:
DOI: 10.2210/pdb8vcr/pdb
PDB entry 8vcr coloured by chain, front view.
PDB entry 8vcr coloured by chain, side view.
PDB entry 8vcr coloured by chain, top view.
Source organisms:
Entry authors: Johnson NV, McLellan JS
Related structures: EMD-43139

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-247672 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Spike protein S2' Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 597 amino acids
Theoretical weight: 65.95 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 697-1208; Coverage: 41%)
Gene names: 2, S
Sequence domains: Coronavirus spike glycoprotein S2
54043-5 Fab Heavy Chain Chains: D, E, H
Molecule details ›
Chains: D, E, H
Length: 233 amino acids
Theoretical weight: 25.13 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
54043-5 Fab Light Chain Chains: F, G, L
Molecule details ›
Chains: F, G, L
Length: 214 amino acids
Theoretical weight: 23.29 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand NAG 15 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3Å
Relevant EMDB volumes: EMD-43139
Expression system: Homo sapiens

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