› 8ve5

Electron Microscopy
3.4Å resolution

(Biarylamine-FT2-WT)1(C10A)3-human transthyretin in the compressed conformation

Released:
DOI: 10.2210/pdb8ve5/pdb
PDB entry 8ve5 coloured by chain, front view.
PDB entry 8ve5 coloured by chain, side view.
PDB entry 8ve5 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Basanta B, Nugroho K, Yan N, Kline GM, Tsai FJ, Wu M, Kelly JW, Lander GC
Related structures: EMD-43165

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136168 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transthyretin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 144 amino acids
Theoretical weight: 15.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02766 (Residues: 21-147; Coverage: 100%)
Gene names: PALB, TTR
Sequence domains: HIUase/Transthyretin family

Ligands and Environments

1 bound ligand:
Ligand P2C 1 x P2C
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.4Å
Relevant EMDB volumes: EMD-43165
Expression system: Escherichia coli

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