› › Function and Biology

Structure of mouse RyR1 (EGTA-only dataset)

Source organism: Mus musculus
Biochemical function: protein binding
Biological process: release of sequestered calcium ion into cytosol
Cellular component: ryanodine receptor complex

Quick links

EC 5.2.1.8: Peptidylprolyl isomerase

Reaction catalysed:
Peptidylproline (omega=180) = peptidylproline (omega=0)
Systematic name:
Peptidylproline cis-trans-isomerase
Alternative Name(s):
  • Cyclophilin
  • PPIase
  • Peptide bond isomerase
  • Peptidyl-prolyl cis-trans isomerase
  • Peptidylprolyl cis-trans isomerase
  • Rotamase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF02026
Domain description: RyR domain
Occurring in:
  1. Ryanodine receptor 1
The deposited structure of PDB entry 8vjj contains 16 copies of Pfam domain PF02026 (RyR domain) in Ryanodine receptor 1. Showing 4 copies in chain A.

PF00622
Domain description: SPRY domain
Occurring in:
  1. Ryanodine receptor 1
The deposited structure of PDB entry 8vjj contains 12 copies of Pfam domain PF00622 (SPRY domain) in Ryanodine receptor 1. Showing 3 copies in chain A.

PF01365
Domain description: RIH domain
Occurring in:
  1. Ryanodine receptor 1
The deposited structure of PDB entry 8vjj contains 8 copies of Pfam domain PF01365 (RIH domain) in Ryanodine receptor 1. Showing 2 copies in chain A.

PF00254
Domain description: FKBP-type peptidyl-prolyl cis-trans isomerase
Occurring in:
  1. Peptidyl-prolyl cis-trans isomerase FKBP1A
The deposited structure of PDB entry 8vjj contains 4 copies of Pfam domain PF00254 (FKBP-type peptidyl-prolyl cis-trans isomerase) in Peptidyl-prolyl cis-trans isomerase FKBP1A. Showing 1 copy in chain B [auth E].

PF00520
Domain description: Ion transport protein
Occurring in:
  1. Ryanodine receptor 1
The deposited structure of PDB entry 8vjj contains 4 copies of Pfam domain PF00520 (Ion transport protein) in Ryanodine receptor 1. Showing 1 copy in chain A.

PF06459
Domain description: Ryanodine Receptor TM 4-6
Occurring in:
  1. Ryanodine receptor 1
The deposited structure of PDB entry 8vjj contains 4 copies of Pfam domain PF06459 (Ryanodine Receptor TM 4-6) in Ryanodine receptor 1. Showing 1 copy in chain A.

PF08454
Domain description: RyR and IP3R Homology associated
Occurring in:
  1. Ryanodine receptor 1
The deposited structure of PDB entry 8vjj contains 4 copies of Pfam domain PF08454 (RyR and IP3R Homology associated) in Ryanodine receptor 1. Showing 1 copy in chain A.

PF21119
Domain description: Ryanodine receptor junctional solenoid repeat
Occurring in:
  1. Ryanodine receptor 1
The deposited structure of PDB entry 8vjj contains 4 copies of Pfam domain PF21119 (Ryanodine receptor junctional solenoid repeat) in Ryanodine receptor 1. Showing 1 copy in chain A.

PF02815
Domain description: MIR domain
Occurring in:
  1. Ryanodine receptor 1
The deposited structure of PDB entry 8vjj contains 4 copies of Pfam domain PF02815 (MIR domain) in Ryanodine receptor 1. Showing 1 copy in chain A.

PF08709
Domain description: Inositol 1,4,5-trisphosphate/ryanodine receptor
Occurring in:
  1. Ryanodine receptor 1
The deposited structure of PDB entry 8vjj contains 4 copies of Pfam domain PF08709 (Inositol 1,4,5-trisphosphate/ryanodine receptor) in Ryanodine receptor 1. Showing 1 copy in chain A.

Quick links