› 8vt7

Electron Microscopy
2.66Å resolution

Structure of the gamma tubulin ring complex nucleated microtubule protofilament.

Released:
DOI: 10.2210/pdb8vt7/pdb
PDB entry 8vt7 coloured by chain, front view.
PDB entry 8vt7 coloured by chain, side view.
PDB entry 8vt7 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of the γ-tubulin ring complex-capped microtubule.
Aher A, Urnavicius L, Xue A, Neselu K, Kapoor TM
Nat Struct Mol Biol (2024)
PMID: 38609661
Related structures: EMD-43519

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-242336 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tubulin beta-3 chain Chains: A, F
Molecule details ›
Chains: A, F
Length: 456 amino acids
Theoretical weight: 51.28 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q13509 (Residues: 1-450; Coverage: 100%)
Gene names: TUBB3, TUBB4
Sequence domains:
Tubulin alpha-1B chain Chains: B, J
Molecule details ›
Chains: B, J
Length: 457 amino acids
Theoretical weight: 51.02 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P68363 (Residues: 1-42, 43-451; Coverage: 100%)
Gene name: TUBA1B
Sequence domains:

Ligands and Environments

3 bound ligands:
Ligand GDP 2 x GDP
Ligand GTP 2 x GTP
Ligand MG 2 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.66Å
Relevant EMDB volumes: EMD-43519
Expression system: Trichoplusia ni

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