8vui

X-ray diffraction
2.1Å resolution

Structure of FabS1CE-EPR-1, an elbow-locked Fab, in complex with the erythropoeitin receptor

Released:
Model geometry
Fit model/data

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-273296 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
S1CE VARIANT OF FAB-EPR-1 heavy chain Chain: A
Molecule details ›
Chain: A
Length: 224 amino acids
Theoretical weight: 24.1 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
S1CE VARIANT OF FAB-EPR-1 light chain Chain: G
Molecule details ›
Chain: G
Length: 212 amino acids
Theoretical weight: 23.05 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Erythropoietin receptor Chain: D

Ligands and Environments

No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P212121
Unit cell:
a: 56.39Å b: 71.93Å c: 197.02Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.197 0.24
Expression system: Homo sapiens