› 8vvy

Electron Microscopy
3.49Å resolution

Human Cullin-1 in complex with CAND2

Released:
DOI: 10.2210/pdb8vvy/pdb
PDB entry 8vvy coloured by chain, front view.
PDB entry 8vvy coloured by chain, side view.
PDB entry 8vvy coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Kenny S, Liu X, Das C
Related structures: EMD-43572

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-284532 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cullin-1 Chain: A
Molecule details ›
Chain: A
Length: 741 amino acids
Theoretical weight: 86.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q13616 (Residues: 13-776; Coverage: 95%)
Gene name: CUL1
Sequence domains:
Cullin-associated NEDD8-dissociated protein 2 Chain: C
Molecule details ›
Chain: C
Length: 1247 amino acids
Theoretical weight: 136.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O75155 (Residues: 1-1236; Coverage: 100%)
Gene names: CAND2, KIAA0667, TIP120B
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.49Å
Relevant EMDB volumes: EMD-43572
Expression system: Escherichia coli BL21(DE3)

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