› 8vxt

Electron Microscopy
4.25Å resolution

Cryo-EM structure of mammalian Thorase filament, 3-layer refinement

Released:
DOI: 10.2210/pdb8vxt/pdb
PDB entry 8vxt coloured by chain, front view.
PDB entry 8vxt coloured by chain, side view.
PDB entry 8vxt coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Cryo-EM Structure of AAA + ATPase Thorase Reveals Novel Helical Filament Formation.
Dar MA, Louder R, Cortes M, Chen R, Ma Q, Chakrabarti M, Umanah GKE, Dawson TM, Dawson VL
Biorxiv (2024)
PMID: 39605435
Related structures: EMD-43639

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-282584 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Outer mitochondrial transmembrane helix translocase Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 321 amino acids
Theoretical weight: 36.23 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9D5T0 (Residues: 41-361; Coverage: 89%)
Gene name: Atad1
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand AGS 6 x AGS
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.25Å
Relevant EMDB volumes: EMD-43639
Expression system: Escherichia coli BL21(DE3)

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