8vy5

X-ray diffraction
2.01Å resolution

Crystal structure of human SAE1

Released:
Model geometry
Fit model/data
Source organism: Homo sapiens
Entry authors: Huang X, Qian J, Yang Y

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-286280 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SUMO-activating enzyme subunit 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 320 amino acids
Theoretical weight: 35.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UBE0 (Residues: 9-346; Coverage: 91%)
Gene names: AOS1, SAE1, SUA1, UBLE1A
Sequence domains: ThiF family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRF BEAMLINE BL10U2
Spacegroup: C2
Unit cell:
a: 103.197Å b: 70.187Å c: 87.591Å
α: 90° β: 108.92° γ: 90°
R-values:
R R work R free
0.233 0.231 0.274
Expression system: Escherichia coli