› 8vyj

Electron Microscopy
3.6Å resolution

Structure of full-length human cardiac sodium channel - Class-I.

Released:
DOI: 10.2210/pdb8vyj/pdb
PDB entry 8vyj coloured by chain, front view.
PDB entry 8vyj coloured by chain, side view.
PDB entry 8vyj coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Biswas R, Chinthalapudi K
Related structures: EMD-43662

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172023 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Sodium channel protein type 5 subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 2016 amino acids
Theoretical weight: 227.15 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q14524 (Residues: 1-2016; Coverage: 100%)
Gene name: SCN5A
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
3 bound ligands:
Ligand 6OU 2 x 6OU
Ligand Y01 7 x Y01
Ligand NAG 3 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.6Å
Relevant EMDB volumes: EMD-43662
Expression system: Homo sapiens

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