› 8w0t

X-ray diffraction
2.5Å resolution

Function and Biology Details

Reaction catalysed: 
Long-chain-acyl-CoA + electron-transfer flavoprotein = long-chain-2,3-dehydroacyl-CoA + reduced electron-transfer flavoprotein
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-246047 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Long-chain specific acyl-CoA dehydrogenase, mitochondrial Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 400 amino acids
Theoretical weight: 44.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P28330 (Residues: 31-430; Coverage: 93%)
Gene name: ACADL
Sequence domains:

Ligands and Environments


Cofactor: Ligand FAD 4 x FAD
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-002
Spacegroup: P212121
Unit cell:
a: 101.143Å b: 102.052Å c: 173.594Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.2 0.262
Expression system: Escherichia coli BL21(DE3)

Quick links