8w2g

Electron Microscopy
3Å resolution

Human liver phosphofructokinase-1 in the R-state conformation

Released:
Source organism: Homo sapiens
Related structures: EMD-43747

Function and Biology Details

Reaction catalysed:
ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6-bisphosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
PDBe Complex ID:
PDB-CPX-148190 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP-dependent 6-phosphofructokinase, liver type Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 780 amino acids
Theoretical weight: 85.12 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
  • Canonical: P17858 (Residues: 1-780; Coverage: 100%)
Gene name: PFKL
Sequence domains: Phosphofructokinase

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution:
Relevant EMDB volumes: EMD-43747
Expression system: unidentified baculovirus