› 8wb3

X-ray diffraction
2.49Å resolution

Human H Chain Ferritin mutant-K86Q with 2 Fe(III)/subunit loading

Released:
DOI: 10.2210/pdb8wb3/pdb
Model geometry
Fit model/data
PDB entry 8wb3 coloured by chain, front view.
PDB entry 8wb3 coloured by chain, side view.
PDB entry 8wb3 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Zhang T, Jiao R

Function and Biology Details

Reaction catalysed: 
4 Fe(2+) + 4 H(+) + O(2) = 4 Fe(3+) + 2 H(2)O
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo 24-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136244 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ferritin heavy chain Chain: A
Molecule details ›
Chain: A
Length: 183 amino acids
Theoretical weight: 21.25 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02794 (Residues: 1-183; Coverage: 100%)
Gene names: FTH, FTH1, FTHL6, OK/SW-cl.84, PIG15
Sequence domains: Ferritin-like domain

Ligands and Environments

2 bound ligands:
Ligand FE 2 x FE
Ligand CA 3 x CA
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRF BEAMLINE BL02U1
Spacegroup: F432
Unit cell:
a: 181.919Å b: 181.919Å c: 181.919Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.187 0.184 0.235
Expression system: Escherichia coli

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