› 8wd9

Electron Microscopy
3.35Å resolution

Cryo-EM structure of Mycobacterium tuberculosis DppABCD in apo form

Released:
DOI: 10.2210/pdb8wd9/pdb
PDB entry 8wd9 coloured by chain, front view.
PDB entry 8wd9 coloured by chain, side view.
PDB entry 8wd9 coloured by chain, top view.
Source organism: Mycobacterium tuberculosis H37Rv
Entry authors: Hu T, Zhang B, Rao Z
Related structures: EMD-37458

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-251484 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
ABC transmembrane type-1 domain-containing protein Chain: B
Molecule details ›
Chain: B
Length: 308 amino acids
Theoretical weight: 32.56 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Mycolicibacterium smegmatis MC2 155
UniProt:
  • Canonical: I6YGV9 (Residues: 1-308; Coverage: 100%)
Gene names: Rv3665c, dppB
Sequence domains:
ABC transmembrane type-1 domain-containing protein Chain: C
Molecule details ›
Chain: C
Length: 287 amino acids
Theoretical weight: 30.49 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Mycolicibacterium smegmatis MC2 155
UniProt:
  • Canonical: L0TEV4 (Residues: 1-266; Coverage: 100%)
Gene names: Rv3664c, dppC
Sequence domains: Binding-protein-dependent transport system inner membrane component
ABC transporter domain-containing protein Chain: D
Molecule details ›
Chain: D
Length: 548 amino acids
Theoretical weight: 59.02 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Mycolicibacterium smegmatis MC2 155
UniProt:
  • Canonical: I6Y482 (Residues: 1-548; Coverage: 100%)
Gene names: Rv3663c, dppD
Sequence domains:
Solute-binding protein family 5 domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 517 amino acids
Theoretical weight: 56.06 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Mycolicibacterium smegmatis MC2 155
UniProt:
  • Canonical: I6X811 (Residues: 25-541; Coverage: 96%)
Gene names: Rv3666c, dppA
Sequence domains: Bacterial extracellular solute-binding proteins, family 5 Middle

Ligands and Environments

2 bound ligands:
Ligand PLM 1 x PLM
Ligand 9XX 1 x 9XX
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.35Å
Relevant EMDB volumes: EMD-37458
Expression system: Mycolicibacterium smegmatis MC2 155

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