› 8wfm

X-ray diffraction
2.99Å resolution

Crystal structure of Omicron BA.1 in complex with a neutralizing antibody scFv T11

Released:
DOI: 10.2210/pdb8wfm/pdb
PDB entry 8wfm coloured by chain, front view.
PDB entry 8wfm coloured by chain, side view.
PDB entry 8wfm coloured by chain, top view.
Source organism: Severe acute respiratory syndrome coronavirus 2
Entry authors: Terekhov SS, Mokrushina YA, Zhang M, Zhang N, Gabibov A, Guo Y

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-535197 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
T11 scFv Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 255 amino acids
Theoretical weight: 26.36 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Trichoplusia
Spike protein S1 Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 223 amino acids
Theoretical weight: 25.42 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Trichoplusia
UniProt:
  • Canonical: P0DTC2 (Residues: 319-541; Coverage: 18%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL10U2
Spacegroup: C2221
Unit cell:
a: 55.41Å b: 172.49Å c: 487.64Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.218 0.215 0.265
Expression system: Trichoplusia

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