› 8wfs

Electron Microscopy
3.36Å resolution

Cryo-EM structure of GPIb-IX Complex

Released:
DOI: 10.2210/pdb8wfs/pdb
PDB entry 8wfs coloured by chain, front view.
PDB entry 8wfs coloured by chain, side view.
PDB entry 8wfs coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Shu ZM, Duan JS, Zhou AW
Related structures: EMD-37498

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero heptamer (preferred)
PDBe Complex ID:
PDB-CPX-283209 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (5 distinct):
Platelet glycoprotein Ib beta chain Chains: B, C, b, c
Molecule details ›
Chains: B, C, b, c
Length: 192 amino acids
Theoretical weight: 20.53 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P13224 (Residues: 26-206; Coverage: 100%)
Gene name: GP1BB
Platelet glycoprotein IX Chains: E, X
Molecule details ›
Chains: E, X
Length: 191 amino acids
Theoretical weight: 20.35 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P14770 (Residues: 17-177; Coverage: 100%)
Gene name: GP9
Sequence domains:
Platelet glycoprotein Ib alpha chain Chain: a
Molecule details ›
Chain: a
Length: 140 amino acids
Theoretical weight: 15.59 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P07359 (Residues: 523-652; Coverage: 20%)
Gene name: GP1BA

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.36Å
Relevant EMDB volumes: EMD-37498
Expression system: Homo sapiens

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