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Structure of DDM1-nucleosome complex in the ADP-BeFx state with DDM1 bound to SHL2 and SHL-2

Source organism: Arabidopsis thaliana
Biochemical function: DNA binding
Biological process: DNA-mediated transformation
Cellular component: nucleus

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EC 3.6.4.12: DNA helicase

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Systematic name:
ATP phosphohydrolase (DNA helix unwinding)
Alternative Name(s):
  • 3' to 5' DNA helicase
  • 3'-5' DNA helicase
  • 3'-5' PfDH
  • 5' to 3' DNA helicase
  • AvDH1
  • BACH1 helicase
  • BLM protein
  • BRCA1-associated C-terminal helicase
  • BcMCM
  • CeWRN-1
  • DNA helicase 120
  • DNA helicase A
  • DNA helicase E
  • DNA helicase II
  • DNA helicase III
  • DNA helicase RECQL5'
  • DNA helicase VI
  • Dbp9p
  • DmRECQ5
  • DnaB
  • DnaB helicase E1
  • HHcsA
  • HPif1
  • Hel E
  • Helicase DnaB
  • Helicase HDH IV
  • Helicase domain of bacteriophage T7 gene 4 protein helicase
  • Hmi1p
  • MCM helicase
  • MCM protein
  • MER3 helicase
  • MER3 protein
  • MPH1
  • PDH120
  • PIF1
  • PcrA
  • PcrA helicase
  • PfDH A
  • Pfh1p
  • UvrD

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF00125
Domain description: Core histone H2A/H2B/H3/H4
Occurring in:
  1. Histone H3.1
  2. Histone H2A.6
  3. Histone H2B.6
The deposited structure of PDB entry 8wha contains 2 copies of Pfam domain PF00125 (Core histone H2A/H2B/H3/H4) in Histone H3.1. Showing 1 copy in chain E.
The deposited structure of PDB entry 8wha contains 2 copies of Pfam domain PF00125 (Core histone H2A/H2B/H3/H4) in Histone H2A.6. Showing 1 copy in chain C.
The deposited structure of PDB entry 8wha contains 2 copies of Pfam domain PF00125 (Core histone H2A/H2B/H3/H4) in Histone H2B.6. Showing 1 copy in chain H.

PF00271
Domain description: Helicase conserved C-terminal domain
Occurring in:
  1. ATP-dependent DNA helicase DDM1
The deposited structure of PDB entry 8wha contains 2 copies of Pfam domain PF00271 (Helicase conserved C-terminal domain) in ATP-dependent DNA helicase DDM1. Showing 1 copy in chain K.

PF00176
Domain description: SNF2-related domain
Occurring in:
  1. ATP-dependent DNA helicase DDM1
The deposited structure of PDB entry 8wha contains 2 copies of Pfam domain PF00176 (SNF2-related domain) in ATP-dependent DNA helicase DDM1. Showing 1 copy in chain K.

PF16211
Domain description: C-terminus of histone H2A
Occurring in:
  1. Histone H2A.6
The deposited structure of PDB entry 8wha contains 2 copies of Pfam domain PF16211 (C-terminus of histone H2A) in Histone H2A.6. Showing 1 copy in chain C.

PF15511
Domain description: Centromere kinetochore component CENP-T histone fold
Occurring in:
  1. Histone H4
The deposited structure of PDB entry 8wha contains 2 copies of Pfam domain PF15511 (Centromere kinetochore component CENP-T histone fold) in Histone H4. Showing 1 copy in chain B.

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