› 8wks

Electron Microscopy
3.58Å resolution

Cryo-EM structure of DSR2-TUBE complex

Released:
DOI: 10.2210/pdb8wks/pdb
PDB entry 8wks coloured by chain, front view.
PDB entry 8wks coloured by chain, side view.
PDB entry 8wks coloured by chain, top view.
Source organisms:
Primary publication:
Molecular basis of bacterial DSR2 anti-phage defense and viral immune evasion.
Huang J, Zhu K, Gao Y, Ye F, Li Z, Ge Y, Liu S, Yang J, Gao A
OpenAccess logo Nat Commun 15 3954 (2024)
PMID: 38729958
Related structures: EMD-37606

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-242752 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
SIR2-like domain-containing protein Chains: A, D, F, H
Molecule details ›
Chains: A, D, F, H
Length: 1004 amino acids
Theoretical weight: 118.44 KDa
Source organism: Bacillus subtilis subsp. natto BEST195
Expression system: Escherichia coli
UniProt:
  • Canonical: D4G637 (Residues: 2-1005; Coverage: 100%)
Gene name: BSNT_07056
Sequence domains: SIR2-like domain
TUBE Chains: B, C, E, G
Molecule details ›
Chains: B, C, E, G
Length: 264 amino acids
Theoretical weight: 29.3 KDa
Source organism: Siphoviridae sp. ct0106
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A162TY69 (Residues: 1-264; Coverage: 100%)
Gene names: B4122_1986, BJQ93_02798, J5227_09585

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.58Å
Relevant EMDB volumes: EMD-37606
Expression system: Escherichia coli

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