Function and Biology

Fzd4/DEP complex

Source organism: Homo sapiens
Biochemical function: Wnt receptor activity
Biological process: Wnt signaling pathway
Cellular component: membrane

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF01534
Domain description: Frizzled/Smoothened family membrane region
Occurring in:
  1. Frizzled-4
The deposited structure of PDB entry 8wm9 contains 2 copies of Pfam domain PF01534 (Frizzled/Smoothened family membrane region) in Frizzled-4. Showing 1 copy in chain A.

PF01392
Domain description: Fz domain
Occurring in:
  1. Frizzled-4
The deposited structure of PDB entry 8wm9 contains 2 copies of Pfam domain PF01392 (Fz domain) in Frizzled-4. Showing 1 copy in chain A (this domain is out of the observed residue ranges!).

PF12316
Domain description: Segment polarity protein dishevelled (Dsh) C terminal
Occurring in:
  1. Segment polarity protein dishevelled homolog DVL-2
The deposited structure of PDB entry 8wm9 contains 1 copy of Pfam domain PF12316 (Segment polarity protein dishevelled (Dsh) C terminal) in Segment polarity protein dishevelled homolog DVL-2. Showing 1 copy in chain C (this domain is out of the observed residue ranges!).

PF00610
Domain description: Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
Occurring in:
  1. Segment polarity protein dishevelled homolog DVL-2
The deposited structure of PDB entry 8wm9 contains 1 copy of Pfam domain PF00610 (Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)) in Segment polarity protein dishevelled homolog DVL-2. Showing 1 copy in chain C.

PF00595
Domain description: PDZ domain
Occurring in:
  1. Segment polarity protein dishevelled homolog DVL-2
The deposited structure of PDB entry 8wm9 contains 1 copy of Pfam domain PF00595 (PDZ domain) in Segment polarity protein dishevelled homolog DVL-2. Showing 1 copy in chain C (this domain is out of the observed residue ranges!).

PF02377
Domain description: Dishevelled specific domain
Occurring in:
  1. Segment polarity protein dishevelled homolog DVL-2
The deposited structure of PDB entry 8wm9 contains 1 copy of Pfam domain PF02377 (Dishevelled specific domain) in Segment polarity protein dishevelled homolog DVL-2. Showing 1 copy in chain C (this domain is out of the observed residue ranges!).

PF00778
Domain description: DIX domain
Occurring in:
  1. Segment polarity protein dishevelled homolog DVL-2
The deposited structure of PDB entry 8wm9 contains 1 copy of Pfam domain PF00778 (DIX domain) in Segment polarity protein dishevelled homolog DVL-2. Showing 1 copy in chain C (this domain is out of the observed residue ranges!).