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Electron Microscopy
3.3Å resolution

Cryo-EM structure of SIR2/HerA complex

Released:
Source organism: Paenibacillus sp. 453mf
Entry authors: Yu G, Liao F, Li X, Li Z, Zhang H
Related structures: EMD-37685

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tridecamer (preferred)
PDBe Complex ID:
PDB-CPX-268909 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Helicase HerA central domain-containing protein Chains: B, D, L, M, N, O
Molecule details ›
Chains: B, D, L, M, N, O
Length: 696 amino acids
Theoretical weight: 77.63 KDa
Source organism: Paenibacillus sp. 453mf
Expression system: Escherichia coli BL21(DE3)
SIR2-like domain-containing protein Chains: J, K, P, Q, R, S, T
Molecule details ›
Chains: J, K, P, Q, R, S, T
Length: 381 amino acids
Theoretical weight: 43.61 KDa
Source organism: Paenibacillus sp. 453mf
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A1I6T0R8 (Residues: 1-381; Coverage: 100%)
Gene name: SAMN04488601_104157
Sequence domains: SIR2-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.3Å
Relevant EMDB volumes: EMD-37685
Expression system: Escherichia coli BL21(DE3)