Function and Biology Details
Reaction catalysed:
Angiotensin II + H(2)O = angiotensin-(1-7) + L-phenylalanine
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-271227 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Angiotensin-converting enzyme
Molecule details ›
Chain: A
Length: 602 amino acids
Theoretical weight: 69.85 KDa
Source organism: Oryctolagus cuniculus
Expression system: Homo sapiens
UniProt:
Sequence domains: Angiotensin-converting enzyme
Length: 602 amino acids
Theoretical weight: 69.85 KDa
Source organism: Oryctolagus cuniculus
Expression system: Homo sapiens
UniProt:
- Canonical:
G1TEF4 (Residues: 19-614; Coverage: 76%)
Sequence domains: Angiotensin-converting enzyme
Spike protein S1
Molecule details ›
Chain: B
Length: 228 amino acids
Theoretical weight: 25.86 KDa
Source organism: Severe acute respiratory syndrome-related coronavirus
Expression system: Homo sapiens
UniProt:
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
Length: 228 amino acids
Theoretical weight: 25.86 KDa
Source organism: Severe acute respiratory syndrome-related coronavirus
Expression system: Homo sapiens
UniProt:
- Canonical: P59594 (Residues: 306-527; Coverage: 18%)
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
