8wq2

Electron Microscopy
4.1Å resolution

Structural basis of translation inhibition by a valine tRNA-derived fragment

Released:
Related structures: EMD-37733

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero 28-mer (preferred)
PDBe Complex ID:
PDB-CPX-271497 (preferred)
Entry contents:
26 distinct polypeptide molecules
2 distinct RNA molecules
Macromolecules (28 distinct):
Small ribosomal subunit protein uS2 Chain: AS2P
Molecule details ›
Chain: AS2P
Length: 196 amino acids
Theoretical weight: 22.47 KDa
Source organism: Sulfolobus acidocaldarius DSM 639
Expression system: Sulfolobus acidocaldarius DSM 639
UniProt:
  • Canonical: P39478 (Residues: 28-223; Coverage: 87%)
Gene names: Saci_0088, nbp1, rps2
Sequence domains: Ribosomal protein S2
Small ribosomal subunit protein eS4 Chain: AS4E
Molecule details ›
Chain: AS4E
Length: 240 amino acids
Theoretical weight: 27.34 KDa
Source organism: Sulfolobus acidocaldarius DSM 639
Expression system: Sulfolobus acidocaldarius DSM 639
UniProt:
  • Canonical: O05634 (Residues: 2-241; Coverage: 98%)
Gene names: Saci_0585, rps4e
Sequence domains:
Small ribosomal subunit protein uS4 Chain: AS4P
Small ribosomal subunit protein uS5 Chain: AS5P
Small ribosomal subunit protein eS6 Chain: AS6E
Small ribosomal subunit protein eS8 Chain: AS8E
Small ribosomal subunit protein uS11 Chain: S11P
Small ribosomal subunit protein uS12 Chain: S12P
Small ribosomal subunit protein uS15 Chain: S15P
Small ribosomal subunit protein uS17 Chain: S17P
Small ribosomal subunit protein eS24 Chain: S24E
Small ribosomal subunit protein eS27 Chain: S27E
Small ribosomal subunit protein eS1 Chain: S3AE
Small ribosomal subunit protein uS3 Chain: AS3P
Small ribosomal subunit protein uS7 Chain: AS7P
Small ribosomal subunit protein uS9 Chain: AS9P
Small ribosomal subunit protein uS10 Chain: S10P
Small ribosomal subunit protein uS13 Chain: S13P
Small ribosomal subunit protein uS14 Chain: S14P
Small ribosomal subunit protein eS17 Chain: S17E
Small ribosomal subunit protein eS19 Chain: S19E
Small ribosomal subunit protein uS19 Chain: S19P
Small ribosomal subunit protein eS31 Chain: S27A
Small ribosomal subunit protein eS28 Chain: S28E
Large ribosomal subunit protein eL8 Chain: SL7A
Small ribosomal subunit protein uS8 Chain: AS8P
RNA (1328-MER) Chain: A16S
RNA (26-MER) Chain: VTRF

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.1Å
Relevant EMDB volumes: EMD-37733
Expression system: Sulfolobus acidocaldarius DSM 639