Function and Biology

Cryo-EM structure of Semliki Forest virus in complex with its receptor VLDLR(2-fold)

Source organisms:
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

EC 3.4.21.90: Togavirin

Reaction catalysed:
Autocatalytic release of the core protein from the N-terminus of the togavirus structural polyprotein by hydrolysis of a -Trp-|-Ser- bond.
Alternative Name(s):
  • NsP2 proteinase
  • Sindbis virus core protein
  • Sindbis virus protease

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF00057
Domain description: Low-density lipoprotein receptor domain class A
Occurring in:
  1. Very low-density lipoprotein receptor
The deposited structure of PDB entry 8x0k contains 4 copies of Pfam domain PF00057 (Low-density lipoprotein receptor domain class A) in Very low-density lipoprotein receptor. Showing 1 copy in chain M [auth D].

PF01589
Domain description: Alphavirus E1 glycoprotein
Occurring in:
  1. Spike glycoprotein E1
The deposited structure of PDB entry 8x0k contains 4 copies of Pfam domain PF01589 (Alphavirus E1 glycoprotein) in p130. Showing 1 copy in chain C.

PF00943
Domain description: Alphavirus E2 glycoprotein
Occurring in:
  1. Spike glycoprotein E2

PF00944
Domain description: Alphavirus core protein
Occurring in:
  1. Capsid protein
The deposited structure of PDB entry 8x0k contains 4 copies of Pfam domain PF00944 (Alphavirus core protein ) in Capsid protein. Showing 1 copy in chain A.