› 8x2a

X-ray diffraction
1.3Å resolution

The Crystal Structure of BMX from Biortus.

Released:
DOI: 10.2210/pdb8x2a/pdb
PDB entry 8x2a coloured by chain, front view.
PDB entry 8x2a coloured by chain, side view.
PDB entry 8x2a coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wang F, Cheng W, Yuan Z, Lin D, Pan W

Function and Biology Details

Reaction catalysed: 
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156424 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytoplasmic tyrosine-protein kinase BMX Chain: A
Molecule details ›
Chain: A
Length: 266 amino acids
Theoretical weight: 30.95 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P51813 (Residues: 411-675; Coverage: 39%)
Gene name: BMX
Sequence domains: Protein tyrosine and serine/threonine kinase

Ligands and Environments

4 bound ligands:
Ligand LTJ 1 x LTJ
Ligand IMD 1 x IMD
Ligand EDO 3 x EDO
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P212121
Unit cell:
a: 55.372Å b: 67.475Å c: 76.519Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.129 0.128 0.161
Expression system: Spodoptera frugiperda

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