› 8x2k

Electron Microscopy
3.03Å resolution

a lipid receptor complex structure

Released:
DOI: 10.2210/pdb8x2k/pdb
PDB entry 8x2k coloured by chain, front view.
PDB entry 8x2k coloured by chain, side view.
PDB entry 8x2k coloured by chain, top view.
Source organisms:
Entry authors: Geng C, Yang D, Jun X
Related structures: EMD-38015

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-245753 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
G-protein coupled receptor 3; Soluble cytochrome b562 Chain: A
Molecule details ›
Chain: A
Length: 466 amino acids
Theoretical weight: 50.45 KDa
Source organisms: Expression system: Spodoptera aff. frugiperda 1 BOLD-2017
UniProt:
  • Canonical: P0ABE7 (Residues: 23-127; Coverage: 99%)
  • Canonical: P46089 (Residues: 1-330; Coverage: 100%)
Gene names: ACCA, GPR3, cybC
Sequence domains:
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Chain: B
Molecule details ›
Chain: B
Length: 373 amino acids
Theoretical weight: 43.39 KDa
Source organism: Homo sapiens
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017
UniProt:
  • Canonical: P63092 (Residues: 26-394; Coverage: 90%)
  • Best match: P63092-2 (Residues: 26-380)
Gene names: GNAS, GNAS1, GSP
Sequence domains: G-protein alpha subunit
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Chain: C
Molecule details ›
Chain: C
Length: 357 amino acids
Theoretical weight: 39.29 KDa
Source organism: Homo sapiens
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017
UniProt:
  • Canonical: P62873 (Residues: 2-340; Coverage: 100%)
Gene name: GNB1
Sequence domains: WD domain, G-beta repeat
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Chain: D
Molecule details ›
Chain: D
Length: 71 amino acids
Theoretical weight: 7.86 KDa
Source organism: Homo sapiens
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017
UniProt:
  • Canonical: P59768 (Residues: 1-71; Coverage: 100%)
Gene name: GNG2
Sequence domains: GGL domain
scfv16 Chain: E
Molecule details ›
Chain: E
Length: 261 amino acids
Theoretical weight: 27.69 KDa
Source organism: Homo sapiens
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017

Ligands and Environments

1 bound ligand:
Ligand 5YM 1 x 5YM
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.03Å
Relevant EMDB volumes: EMD-38015
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017

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