PDB 8x91 structure summary ‹ Protein Data Bank in Europe (PDBe)

Function and Biology Details

Biochemical function:

calcium channel regulator activity

Biological process:

calcium ion transmembrane transport

Cellular component:

synapse

Structure analysis Details

Assembly composition:

hetero tetramer (preferred)

PDBe Complex ID:

PDB-CPX-241857 (preferred)

Entry contents:

4 distinct polypeptide molecules

Macromolecules (7 distinct):

Voltage-dependent L-type calcium channel subunit beta-3 Chain: C

Molecule details ›

Chain: C
Length: 496 amino acids
Theoretical weight: 56.23 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:

Canonical: P54284 (Residues: 1-484; Coverage: 100%)

Gene names: CACNB3, CACNLB3
Sequence domains:

Omega-conotoxin MVIIC Chain: X

Molecule details ›

Chain: X
Length: 26 amino acids
Theoretical weight: 2.76 KDa
Source organism: Conus magus
Expression system: Not provided
UniProt:

Canonical: P37300 (Residues: 3-28; Coverage: 90%)

Voltage-dependent calcium channel subunit alpha-2/delta-1 Chain: B

Molecule details ›

Chain: B
Length: 1115 amino acids
Theoretical weight: 126.32 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:

Canonical: P54289 (Residues: 1-1103; Coverage: 100%)

Gene names: CACNA2D1, CACNL2A, CCHL2A, MHS3
Sequence domains:

Voltage-dependent P/Q-type calcium channel subunit alpha-1A Chain: A

Molecule details ›

Chain: A
Length: 2549 amino acids
Theoretical weight: 287.53 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt: