8xa0

Electron Microscopy
4Å resolution

penton capsomer of the VZV C-capsid

Released:

Function and Biology Details

Reaction catalysed:
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
hetero tridecamer (preferred)
PDBe Complex ID:
PDB-CPX-283212 (preferred)
Entry contents:
7 distinct polypeptide molecules
Macromolecules (7 distinct):
Large tegument protein deneddylase Chains: 2, y
Molecule details ›
Chains: 2, y
Length: 47 amino acids
Theoretical weight: 5.5 KDa
Source organism: Human alphaherpesvirus 3
Expression system: Homo sapiens
UniProt:
  • Canonical: P10220 (Residues: 3117-3163; Coverage: 2%)
Gene name: UL36
ORF40 Chains: A, C, E, F, G
Molecule details ›
Chains: A, C, E, F, G
Length: 1370 amino acids
Theoretical weight: 152.37 KDa
Source organism: Human alphaherpesvirus 3
Expression system: Homo sapiens
UniProt:
  • Canonical: Q6QCL5 (Residues: 25-1394; Coverage: 98%)
Gene names: HHV3_E_SVETAgp42, HHV3_gp42, HHV3gp42, ORF 40, ORF40
Sequence domains: Herpes virus major capsid protein
Capsid vertex component 1 Chain: h
Capsid vertex component 2 Chains: q, u
Triplex capsid protein 2 Chain: R
Triplex capsid protein 2 Chain: V
Triplex capsid protein 1 Chain: Z

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution:
Relevant EMDB volumes: EMD-38190
Expression system: Homo sapiens