› 8xbs

Electron Microscopy
2.21Å resolution

C. elegans apo-SID1 structure

Released:
DOI: 10.2210/pdb8xbs/pdb
PDB entry 8xbs coloured by chain, front view.
PDB entry 8xbs coloured by chain, side view.
PDB entry 8xbs coloured by chain, top view.
Source organism: Caenorhabditis elegans
Primary publication:
Structural basis for double-stranded RNA recognition by SID1.
Wang R, Cong Y, Qian D, Yan C, Gong D
OpenAccess logo Nucleic Acids Res (2024)
PMID: 38742627
Related structures: EMD-38227

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-236134 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Systemic RNA interference defective protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 792 amino acids
Theoretical weight: 90.08 KDa
Source organism: Caenorhabditis elegans
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9GZC8 (Residues: 18-776; Coverage: 100%)
Gene names: C04F5.1, rde-7, rsd-8, sid-1
Sequence domains: dsRNA-gated channel SID-1

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
4 bound ligands:
Ligand ZN 2 x ZN
Ligand CLR 8 x CLR
Ligand POV 2 x POV
Ligand NAG 2 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.21Å
Relevant EMDB volumes: EMD-38227
Expression system: Homo sapiens

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