› 8xfl

X-ray diffraction
3Å resolution

The Crystal Structure of MARK4 from Biortus.

Released:
DOI: 10.2210/pdb8xfl/pdb
PDB entry 8xfl coloured by chain, front view.
PDB entry 8xfl coloured by chain, side view.
PDB entry 8xfl coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wang F, Cheng W, Yuan Z, Qi J, Li J

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188605 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
MAP/microtubule affinity-regulating kinase 4 Chains: A, B
Molecule details ›
Chains: A, B
Length: 327 amino acids
Theoretical weight: 37.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96L34 (Residues: 44-370; Coverage: 44%)
Gene names: KIAA1860, MARK4, MARKL1
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL45XU
Spacegroup: C2
Unit cell:
a: 114.447Å b: 78.103Å c: 86.155Å
α: 90° β: 122° γ: 90°
R-values:
R R work R free
0.21 0.207 0.27
Expression system: Escherichia coli

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