8xm7

Electron Microscopy
4.91Å resolution

Cryo-EM structure of the RhoG/DOCK5/ELMO1/Rac1 complex: RhoG/DOCK5/ELMO1 focused map

Released:

Function and Biology Details

Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-274206 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Engulfment and cell motility protein 1 Chain: A
Molecule details ›
Chain: A
Length: 733 amino acids
Theoretical weight: 84.34 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q92556 (Residues: 1-727; Coverage: 100%)
Gene names: ELMO1, KIAA0281
Sequence domains:
Dedicator of cytokinesis protein 5 Chain: B
Molecule details ›
Chain: B
Length: 1648 amino acids
Theoretical weight: 191.49 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9H7D0 (Residues: 1-1642; Coverage: 88%)
Gene name: DOCK5
Sequence domains:
Rho-related GTP-binding protein RhoG Chain: D

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.91Å
Relevant EMDB volumes: EMD-38466
Expression systems:
  • Homo sapiens
  • Escherichia coli