Function and Biology Details
Reaction catalysed:
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Structure analysis Details
Assembly composition:
hetero 37-mer (preferred)
PDBe Complex ID:
PDB-CPX-281481 (preferred)
Entry contents:
36 distinct polypeptide molecules
1 distinct RNA molecule
1 distinct RNA molecule
Macromolecules (37 distinct):
Small ribosomal subunit protein eS32
Chain: Ln
Molecule details ›
Chain: Ln
Length: 25 amino acids
Theoretical weight: 3.47 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Ribosomal protein L41
Length: 25 amino acids
Theoretical weight: 3.47 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62945 (Residues: 1-25; Coverage: 100%)
Sequence domains: Ribosomal protein L41
Small ribosomal subunit protein uS2
Chain: SA
Molecule details ›
Chain: SA
Length: 295 amino acids
Theoretical weight: 32.88 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 295 amino acids
Theoretical weight: 32.88 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P08865 (Residues: 1-295; Coverage: 100%)
Sequence domains:
Small ribosomal subunit protein eS1
Chain: SB
Molecule details ›
Chain: SB
Length: 264 amino acids
Theoretical weight: 30 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Ribosomal S3Ae family
Length: 264 amino acids
Theoretical weight: 30 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P61247 (Residues: 1-264; Coverage: 100%)
Sequence domains: Ribosomal S3Ae family
Small ribosomal subunit protein uS3
Chain: SD
Molecule details ›
Chain: SD
Length: 243 amino acids
Theoretical weight: 26.73 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 243 amino acids
Theoretical weight: 26.73 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P23396 (Residues: 1-243; Coverage: 100%)
Sequence domains:
Small ribosomal subunit protein eS4, X isoform
Chain: SE
Molecule details ›
Small ribosomal subunit protein uS7
Chain: SF
Molecule details ›
Chain: SF
Length: 204 amino acids
Theoretical weight: 22.91 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Ribosomal protein S7p/S5e
Length: 204 amino acids
Theoretical weight: 22.91 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P46782 (Residues: 1-204; Coverage: 100%)
Sequence domains: Ribosomal protein S7p/S5e
Small ribosomal subunit protein eS7
Chain: SH
Molecule details ›
Chain: SH
Length: 194 amino acids
Theoretical weight: 22.17 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Ribosomal protein S7e
Length: 194 amino acids
Theoretical weight: 22.17 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62081 (Residues: 1-194; Coverage: 100%)
Sequence domains: Ribosomal protein S7e
Small ribosomal subunit protein eS8
Chain: SI
Molecule details ›
Chain: SI
Length: 208 amino acids
Theoretical weight: 24.26 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Ribosomal protein S8e
Length: 208 amino acids
Theoretical weight: 24.26 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62241 (Residues: 1-208; Coverage: 100%)
Sequence domains: Ribosomal protein S8e
Small ribosomal subunit protein eS10
Chain: SK
Molecule details ›
Chain: SK
Length: 165 amino acids
Theoretical weight: 18.93 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Plectin/S10 domain
Length: 165 amino acids
Theoretical weight: 18.93 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P46783 (Residues: 1-165; Coverage: 100%)
Sequence domains: Plectin/S10 domain
Small ribosomal subunit protein uS17
Chain: SL
Molecule details ›
Chain: SL
Length: 158 amino acids
Theoretical weight: 18.47 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 158 amino acids
Theoretical weight: 18.47 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62280 (Residues: 1-158; Coverage: 100%)
Sequence domains:
Small ribosomal subunit protein uS19
Chain: SP
Molecule details ›
Chain: SP
Length: 145 amino acids
Theoretical weight: 17.08 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Ribosomal protein S19
Length: 145 amino acids
Theoretical weight: 17.08 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62841 (Residues: 1-145; Coverage: 100%)
Sequence domains: Ribosomal protein S19
Small ribosomal subunit protein uS9
Chain: SQ
Molecule details ›
Chain: SQ
Length: 146 amino acids
Theoretical weight: 16.48 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Ribosomal protein S9/S16
Length: 146 amino acids
Theoretical weight: 16.48 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62249 (Residues: 1-146; Coverage: 100%)
Sequence domains: Ribosomal protein S9/S16
Small ribosomal subunit protein eS17
Chain: SR
Molecule details ›
Chain: SR
Length: 135 amino acids
Theoretical weight: 15.58 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Ribosomal S17
Length: 135 amino acids
Theoretical weight: 15.58 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P08708 (Residues: 1-135; Coverage: 100%)
Sequence domains: Ribosomal S17
Small ribosomal subunit protein uS13
Chain: SS
Molecule details ›
Chain: SS
Length: 152 amino acids
Theoretical weight: 17.76 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Ribosomal protein S13/S18
Length: 152 amino acids
Theoretical weight: 17.76 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62269 (Residues: 1-152; Coverage: 100%)
Sequence domains: Ribosomal protein S13/S18
Small ribosomal subunit protein eS19
Chain: ST
Molecule details ›
Chain: ST
Length: 145 amino acids
Theoretical weight: 16.09 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Ribosomal protein S19e
Length: 145 amino acids
Theoretical weight: 16.09 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P39019 (Residues: 1-145; Coverage: 100%)
Sequence domains: Ribosomal protein S19e
Small ribosomal subunit protein uS10
Chain: SU
Molecule details ›
Chain: SU
Length: 119 amino acids
Theoretical weight: 13.4 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Ribosomal protein S10p/S20e
Length: 119 amino acids
Theoretical weight: 13.4 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P60866 (Residues: 1-119; Coverage: 100%)
Sequence domains: Ribosomal protein S10p/S20e
Small ribosomal subunit protein eS21
Chain: SV
Molecule details ›
Chain: SV
Length: 83 amino acids
Theoretical weight: 9.12 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Ribosomal protein S21e
Length: 83 amino acids
Theoretical weight: 9.12 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P63220 (Residues: 1-83; Coverage: 100%)
Sequence domains: Ribosomal protein S21e
Small ribosomal subunit protein uS12
Chain: SX
Molecule details ›
Chain: SX
Length: 143 amino acids
Theoretical weight: 15.84 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Ribosomal protein S12/S23
Length: 143 amino acids
Theoretical weight: 15.84 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62266 (Residues: 1-143; Coverage: 100%)
Sequence domains: Ribosomal protein S12/S23
Small ribosomal subunit protein eS26
Chain: Sa
Molecule details ›
Chain: Sa
Length: 115 amino acids
Theoretical weight: 13.05 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Ribosomal protein S26e
Length: 115 amino acids
Theoretical weight: 13.05 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62854 (Residues: 1-115; Coverage: 100%)
Sequence domains: Ribosomal protein S26e
Small ribosomal subunit protein eS28
Chain: Sc
Molecule details ›
Chain: Sc
Length: 69 amino acids
Theoretical weight: 7.86 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Ribosomal protein S28e
Length: 69 amino acids
Theoretical weight: 7.86 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62857 (Residues: 1-69; Coverage: 100%)
Sequence domains: Ribosomal protein S28e
Small ribosomal subunit protein uS14
Chain: Sd
Molecule details ›
Chain: Sd
Length: 56 amino acids
Theoretical weight: 6.69 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Ribosomal protein S14p/S29e
Length: 56 amino acids
Theoretical weight: 6.69 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62273 (Residues: 1-56; Coverage: 100%)
Sequence domains: Ribosomal protein S14p/S29e
Small ribosomal subunit protein RACK1
Chain: Sg
Molecule details ›
Chain: Sg
Length: 317 amino acids
Theoretical weight: 35.12 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: WD domain, G-beta repeat
Length: 317 amino acids
Theoretical weight: 35.12 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P63244 (Residues: 1-317; Coverage: 100%)
Sequence domains: WD domain, G-beta repeat
Small ribosomal subunit protein uS5
Chain: SC
Molecule details ›
Chain: SC
Length: 293 amino acids
Theoretical weight: 31.38 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 293 amino acids
Theoretical weight: 31.38 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P15880 (Residues: 1-293; Coverage: 100%)
Sequence domains:
Small ribosomal subunit protein eS6
Chain: SG
Molecule details ›
Chain: SG
Length: 249 amino acids
Theoretical weight: 28.75 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Ribosomal protein S6e
Length: 249 amino acids
Theoretical weight: 28.75 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62753 (Residues: 1-249; Coverage: 100%)
Sequence domains: Ribosomal protein S6e
Small ribosomal subunit protein uS4
Chain: SJ
Molecule details ›
Chain: SJ
Length: 194 amino acids
Theoretical weight: 22.64 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 194 amino acids
Theoretical weight: 22.64 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P46781 (Residues: 1-194; Coverage: 100%)
Sequence domains:
Small ribosomal subunit protein eS12
Chain: SM
Molecule details ›
Chain: SM
Length: 132 amino acids
Theoretical weight: 14.54 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Length: 132 amino acids
Theoretical weight: 14.54 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P25398 (Residues: 1-132; Coverage: 100%)
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Small ribosomal subunit protein uS15
Chain: SN
Molecule details ›
Chain: SN
Length: 151 amino acids
Theoretical weight: 17.26 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 151 amino acids
Theoretical weight: 17.26 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62277 (Residues: 1-151; Coverage: 100%)
Sequence domains:
Small ribosomal subunit protein uS11
Chain: SO
Molecule details ›
Chain: SO
Length: 151 amino acids
Theoretical weight: 16.3 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Ribosomal protein S11
Length: 151 amino acids
Theoretical weight: 16.3 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62263 (Residues: 1-151; Coverage: 100%)
Sequence domains: Ribosomal protein S11
Small ribosomal subunit protein uS8
Chain: SW
Molecule details ›
Chain: SW
Length: 130 amino acids
Theoretical weight: 14.87 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Ribosomal protein S8
Length: 130 amino acids
Theoretical weight: 14.87 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62244 (Residues: 1-130; Coverage: 100%)
Sequence domains: Ribosomal protein S8
Small ribosomal subunit protein eS24
Chain: SY
Molecule details ›
Chain: SY
Length: 133 amino acids
Theoretical weight: 15.46 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Ribosomal protein S24e
Length: 133 amino acids
Theoretical weight: 15.46 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62847 (Residues: 1-133; Coverage: 100%)
Sequence domains: Ribosomal protein S24e
Small ribosomal subunit protein eS25
Chain: SZ
Molecule details ›
Chain: SZ
Length: 125 amino acids
Theoretical weight: 13.78 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: S25 ribosomal protein
Length: 125 amino acids
Theoretical weight: 13.78 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62851 (Residues: 1-125; Coverage: 100%)
Sequence domains: S25 ribosomal protein
Small ribosomal subunit protein eS27
Chain: Sb
Molecule details ›
Chain: Sb
Length: 84 amino acids
Theoretical weight: 9.48 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Ribosomal protein S27
Length: 84 amino acids
Theoretical weight: 9.48 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P42677 (Residues: 1-84; Coverage: 100%)
Sequence domains: Ribosomal protein S27
Small ribosomal subunit protein eS30
Chain: Se
Molecule details ›
Chain: Se
Length: 59 amino acids
Theoretical weight: 6.67 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Ribosomal protein S30
Length: 59 amino acids
Theoretical weight: 6.67 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62861 (Residues: 75-133; Coverage: 44%)
Sequence domains: Ribosomal protein S30
Ubiquitin-ribosomal protein eS31 fusion protein
Chain: Sf
Molecule details ›
Chain: Sf
Length: 156 amino acids
Theoretical weight: 18 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 156 amino acids
Theoretical weight: 18 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62979 (Residues: 1-156; Coverage: 100%)
Sequence domains:
La-related protein 1
Chain: JD
Molecule details ›
Chain: JD
Length: 1096 amino acids
Theoretical weight: 123.71 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 1096 amino acids
Theoretical weight: 123.71 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: Q6PKG0 (Residues: 1-1096; Coverage: 100%)
Sequence domains:
Leucine-rich repeat-containing protein 47
Chain: JC
Molecule details ›
Chain: JC
Length: 583 amino acids
Theoretical weight: 63.56 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 583 amino acids
Theoretical weight: 63.56 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: Q8N1G4 (Residues: 1-583; Coverage: 100%)
Sequence domains:
18S Ribosomal RNA
Chain: S2
Molecule details ›
Chain: S2
Length: 1869 nucleotides
Theoretical weight: 602.75 KDa
Length: 1869 nucleotides
Theoretical weight: 602.75 KDa