› 8xuq

Electron Microscopy
3.17Å resolution

Cryo-EM structure of tomato NRC2 tetramer

Released:
DOI: 10.2210/pdb8xuq/pdb
PDB entry 8xuq coloured by chain, front view.
PDB entry 8xuq coloured by chain, side view.
PDB entry 8xuq coloured by chain, top view.
Source organism: Solanum lycopersicum
Primary publication:
Oligomerization-mediated autoinhibition and cofactor binding of a plant NLR.
Ma S, An C, Lawson AW, Cao Y, Sun Y, Tan EYJ, Pan J, Jirschitzka J, Kümmel F, Mukhi N, Han Z, Feng S, Wu B, Schulze-Lefert P, Chai J
Nature (2024)
PMID: 38866053
Related structures: EMD-38680

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-244479 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NRC1 Chains: A, E, F, G
Molecule details ›
Chains: A, E, F, G
Length: 885 amino acids
Theoretical weight: 101.33 KDa
Source organism: Solanum lycopersicum
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: A0A3Q7IF17 (Residues: 1-885; Coverage: 100%)
Gene name: 101243750
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand IHP 4 x IHP
Ligand ADP 4 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.17Å
Relevant EMDB volumes: EMD-38680
Expression system: Spodoptera frugiperda

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