› 8xvz

Electron Microscopy
3.78Å resolution

Cryo-EM structure of OSCA3.1-2E(R611E-R619E)-closed/'desensitized' state

Released:
DOI: 10.2210/pdb8xvz/pdb
PDB entry 8xvz coloured by chain, front view.
PDB entry 8xvz coloured by chain, side view.
PDB entry 8xvz coloured by chain, top view.
Source organism: Arabidopsis thaliana
Primary publication:
Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Han Y, Zhou Z, Jin R, Dai F, Ge Y, Ju X, Ma X, He S, Yuan L, Wang Y, Yang W, Yue X, Chen Z, Sun Y, Corry B, Cox CD, Zhang Y
Nature (2024)
PMID: 38570680
Related structures: EMD-38724

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189929 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CSC1-like protein ERD4 Chains: A, B
Molecule details ›
Chains: A, B
Length: 730 amino acids
Theoretical weight: 82.59 KDa
Source organism: Arabidopsis thaliana
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9C8G5 (Residues: 1-724; Coverage: 100%)
Gene names: At1g30360, ERD4, OSCA3.1, T4K22.4
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.78Å
Relevant EMDB volumes: EMD-38724
Expression system: Homo sapiens

Quick links