› 8xwa

Electron Microscopy
3.48Å resolution

Structure of CXCR2 bound to CXCL1 (Ligand-receptor focused map)

Released:
DOI: 10.2210/pdb8xwa/pdb
PDB entry 8xwa coloured by chain, front view.
PDB entry 8xwa coloured by chain, side view.
PDB entry 8xwa coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Sano FK, Saha S, Sharma S, Ganguly M, Shihoya W, Nureki O, Shukla AK, Banerjee R
Related structures: EMD-38732

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-283871 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Growth-regulated alpha protein Chains: D, E
Molecule details ›
Chains: D, E
Length: 73 amino acids
Theoretical weight: 7.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09341 (Residues: 35-107; Coverage: 100%)
Gene names: CXCL1, GRO, GRO1, GROA, MGSA, SCYB1
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
C-X-C chemokine receptor type 2 Chain: R
Molecule details ›
Chain: R
Length: 416 amino acids
Theoretical weight: 46.7 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P25025 (Residues: 2-360; Coverage: 100%)
Gene names: CXCR2, IL8RB
Sequence domains: 7 transmembrane receptor (rhodopsin family)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.48Å
Relevant EMDB volumes: EMD-38732
Expression systems:
  • Escherichia coli
  • Spodoptera frugiperda

Quick links