8xx1

X-ray diffraction
2.55Å resolution

The Crystal Structure of MAPKAP kinase 2 domain from Biortus

Released:
Model geometry
Fit model/data
Source organism: Homo sapiens
Entry authors: Wang F, Cheng W, Lv Z, Ju C, Ni C

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-155865 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
MAP kinase-activated protein kinase 2 Chain: A
Molecule details ›
Chain: A
Length: 318 amino acids
Theoretical weight: 36.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P49137 (Residues: 47-364; Coverage: 80%)
Gene name: MAPKAPK2
Sequence domains: Protein kinase domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P6322
Unit cell:
a: 103.239Å b: 103.239Å c: 166.788Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.17 0.166 0.245
Expression system: Escherichia coli