› 8xxx

Electron Microscopy
3.17Å resolution

Structure of CXCR2 bound to CXCL6 (Composite map)

Released:
DOI: 10.2210/pdb8xxx/pdb
PDB entry 8xxx coloured by chain, front view.
PDB entry 8xxx coloured by chain, side view.
PDB entry 8xxx coloured by chain, top view.
Source organisms:
Entry authors: Sano FK, Saha S, Sharma S, Ganguly M, Shihoya W, Nureki O, Shukla AK, Banerjee R
Related structures: EMD-38764

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-283875 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (6 distinct):
C-X-C motif chemokine 6 Chain: D
Molecule details ›
Chain: D
Length: 77 amino acids
Theoretical weight: 8.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P80162 (Residues: 38-114; Coverage: 100%)
Gene names: CXCL6, GCP2, SCYB6
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
C-X-C chemokine receptor type 2 Chain: R
Molecule details ›
Chain: R
Length: 416 amino acids
Theoretical weight: 46.7 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P25025 (Residues: 2-360; Coverage: 100%)
Gene names: CXCR2, IL8RB
Sequence domains: 7 transmembrane receptor (rhodopsin family)
Guanine nucleotide-binding protein G(o) subunit alpha Chain: A
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Chain: B
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Chain: G
Antibody fragment ScFv16 Chain: S

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 3.17Å
Relevant EMDB volumes: EMD-38764
Expression systems:
  • Escherichia coli
  • Spodoptera frugiperda

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