Function and Biology Details
Reaction catalysed:
Angiotensin II + H(2)O = angiotensin-(1-7) + L-phenylalanine
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-144194 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Processed angiotensin-converting enzyme 2
Molecule details ›
Chains: A, B
Length: 598 amino acids
Theoretical weight: 69.25 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: Angiotensin-converting enzyme
Length: 598 amino acids
Theoretical weight: 69.25 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
Q9BYF1 (Residues: 19-614; Coverage: 76%)
Sequence domains: Angiotensin-converting enzyme
Spike protein S1
Molecule details ›
Chains: C, D
Length: 194 amino acids
Theoretical weight: 21.94 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Trichoplusia ni
UniProt:
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
Length: 194 amino acids
Theoretical weight: 21.94 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Trichoplusia ni
UniProt:
- Canonical: P0DTC2 (Residues: 333-526; Coverage: 15%)
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
Ligands and Environments
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
SSRF BEAMLINE BL19U1
Spacegroup:
P21
Expression system: Trichoplusia ni
