› 8y0p

X-ray diffraction
2.62Å resolution

Beta-Catenin in complex with peptide 301

Released:
DOI: 10.2210/pdb8y0p/pdb
PDB entry 8y0p coloured by chain, front view.
PDB entry 8y0p coloured by chain, side view.
PDB entry 8y0p coloured by chain, top view.
Source organism: Homo sapiens
Entry author: Tim F

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
monomeric
Assembly name:
PDBe Complex ID:
PDB-CPX-126327 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Catenin beta-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 549 amino acids
Theoretical weight: 60.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P35222 (Residues: 138-686; Coverage: 70%)
Gene names: CTNNB, CTNNB1, OK/SW-cl.35, PRO2286
Sequence domains: Armadillo/beta-catenin-like repeat
B-cell CLL/lymphoma 9 protein Chain: L
Molecule details ›
Chain: L
Length: 24 amino acids
Theoretical weight: 3.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O00512 (Residues: 351-374; Coverage: 2%)
Gene name: BCL9
Sequence domains: B-cell lymphoma 9 protein

Ligands and Environments

1 bound ligand:
Ligand PRO 4 x PRO
1 modified residue:
Ligand NAL 1 x NAL

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: P212121
Unit cell:
a: 63.921Å b: 100.758Å c: 187.32Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.241 0.239 0.279
Expression system: Escherichia coli

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