› 8y32

Electron Microscopy
4.13Å resolution

BA.2.86-V483 RBD in complex with bACE2

Released:
DOI: 10.2210/pdb8y32/pdb
PDB entry 8y32 coloured by chain, front view.
PDB entry 8y32 coloured by chain, side view.
PDB entry 8y32 coloured by chain, top view.
Source organisms:
Entry authors: Yue C, Liu P
Related structures: EMD-38866

Function and Biology Details

Reaction catalysed: 
Angiotensin II + H(2)O = angiotensin-(1-7) + L-phenylalanine
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-281516 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Angiotensin-converting enzyme Chain: A
Molecule details ›
Chain: A
Length: 786 amino acids
Theoretical weight: 91.31 KDa
Source organism: Bos taurus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2HJI5 (Residues: 19-804; Coverage: 100%)
Gene name: ACE2
Sequence domains:
Spike protein S1 Chain: B
Molecule details ›
Chain: B
Length: 211 amino acids
Theoretical weight: 23.98 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 331-541; Coverage: 17%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding

Ligands and Environments

2 bound ligands:
Ligand CL 1 x CL
Ligand NAG 7 x NAG
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 4.13Å
Relevant EMDB volumes: EMD-38866
Expression system: Homo sapiens

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