› 8y4c

Electron Microscopy
3.75Å resolution

BA.2.86 S-trimer in complex with Nab XGv280

Released:
DOI: 10.2210/pdb8y4c/pdb
PDB entry 8y4c coloured by chain, front view.
PDB entry 8y4c coloured by chain, side view.
PDB entry 8y4c coloured by chain, top view.
Source organisms:
Primary publication:
Enhancing RBD exposure and S1 shedding by an extremely conserved SARS-CoV-2 NTD epitope.
Zhu Q, Liu P, Liu S, Yue C, Wang X
Signal Transduct Target Ther 9 217 (2024)
PMID: 39191733
Related structures: EMD-38915

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-273056 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1204 amino acids
Theoretical weight: 133.87 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-16, 17-1208; Coverage: 94%)
Gene names: 2, S
Sequence domains:
XGv280 Heavy chain Chains: D, E, H
Molecule details ›
Chains: D, E, H
Length: 126 amino acids
Theoretical weight: 13.74 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
XGv280 Light chain Chains: F, G, L
Molecule details ›
Chains: F, G, L
Length: 111 amino acids
Theoretical weight: 11.56 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

1 bound ligand:
Ligand NAG 54 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.75Å
Relevant EMDB volumes: EMD-38915
Expression system: Homo sapiens

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