› 8y8v

Electron Microscopy
2.49Å resolution

Cryo-EM structure of AQP7 in POPC nanodisc

Released:
DOI: 10.2210/pdb8y8v/pdb
PDB entry 8y8v coloured by chain, front view.
PDB entry 8y8v coloured by chain, side view.
PDB entry 8y8v coloured by chain, top view.
Source organisms:
Primary publication:
Narrowed pore conformations of aquaglyceroporins AQP3 and GlpF.
Kozai D, Inoue M, Suzuki S, Kamegawa A, Nishikawa K, Suzuki H, Ekimoto T, Ikeguchi M, Fujiyoshi Y
Nat Commun 16 2653 (2025)
PMID: 40113770
Related structures: EMD-39060

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-290532 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aquaporin-7; Green fluorescent protein Chain: A
Molecule details ›
Chain: A
Length: 607 amino acids
Theoretical weight: 67.26 KDa
Source organisms: Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P42212 (Residues: 2-238; Coverage: 100%)
  • Canonical: O14520 (Residues: 1-342; Coverage: 100%)
Gene names: AQP7, AQP7L, AQP9, GFP
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand P5S 1 x P5S
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 2.49Å
Relevant EMDB volumes: EMD-39060
Expression system: Spodoptera frugiperda

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