8yat

X-ray diffraction
3.94Å resolution

SOD1, Nanobody1, Nanobody2 and Nanobody3 complex

Released:
Model geometry
Fit model/data
Entry author: Cheng S

Function and Biology Details

Reaction catalysed:
2 superoxide + 2 H(+) = O(2) + H(2)O(2)
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-285158 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Superoxide dismutase [Cu-Zn] Chains: A, E, I, M
Molecule details ›
Chains: A, E, I, M
Length: 153 amino acids
Theoretical weight: 15.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P00441 (Residues: 2-154; Coverage: 99%)
Gene name: SOD1
Sequence domains: Copper/zinc superoxide dismutase (SODC)
NB1 Chains: B, F, J, N
Molecule details ›
Chains: B, F, J, N
Length: 117 amino acids
Theoretical weight: 12.56 KDa
Source organism: Vicugna pacos
Expression system: Escherichia coli
NB2 Chains: C, G, K, O
NB3 Chains: D, H, L, P

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRF BEAMLINE BL02U1
Spacegroup: P212121
Unit cell:
a: 377.129Å b: 46.672Å c: 156.949Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.308 0.303 0.368
Expression system: Escherichia coli