› 8yf1

Electron Microscopy
3.38Å resolution

Cryo-EM structure of human SV2A in complex with Brivaracetam

Released:
DOI: 10.2210/pdb8yf1/pdb
PDB entry 8yf1 coloured by chain, front view.
PDB entry 8yf1 coloured by chain, side view.
PDB entry 8yf1 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Qu Q, Liu S, Zhou Z
Related structures: EMD-39207

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-243815 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Synaptic vesicle glycoprotein 2A Chains: A, B
Molecule details ›
Chains: A, B
Length: 755 amino acids
Theoretical weight: 84.39 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q7L0J3 (Residues: 1-734; Coverage: 99%)
Gene names: KIAA0736, PSEC0174, SV2A
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand VLX 2 x VLX
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.38Å
Relevant EMDB volumes: EMD-39207
Expression system: Homo sapiens

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