8yfc

Electron Microscopy
3.2Å resolution

Human PIEZO1-A1988V-MDFIC

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-284020 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Piezo-type mechanosensitive ion channel component 1 Chains: A, B, D
Molecule details ›
Chains: A, B, D
Length: 2521 amino acids
Theoretical weight: 287.09 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q92508 (Residues: 1-2521; Coverage: 100%)
Gene names: FAM38A, KIAA0233, PIEZO1
Sequence domains:
MyoD family inhibitor domain-containing protein Chains: C, E, F
Molecule details ›
Chains: C, E, F
Length: 246 amino acids
Theoretical weight: 25.81 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9P1T7 (Residues: 1-246; Coverage: 100%)
Gene name: MDFIC
Sequence domains: MyoD family inhibitor

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 3.2Å
Relevant EMDB volumes: EMD-39219
Expression system: Homo sapiens