› 8yhh

X-ray diffraction
1.95Å resolution

The Crystal Structure of Mitotic Kinesin Eg5 from Biortus

Released:
DOI: 10.2210/pdb8yhh/pdb
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PDB entry 8yhh coloured by chain, front view.
PDB entry 8yhh coloured by chain, side view.
PDB entry 8yhh coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wang F, Cheng W, Lv Z, Qi J, Wu B

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156614 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kinesin-like protein KIF11 Chains: A, B
Molecule details ›
Chains: A, B
Length: 370 amino acids
Theoretical weight: 41.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P52732 (Residues: 1-368; Coverage: 35%)
Gene names: EG5, KIF11, KNSL1, TRIP5
Sequence domains: Kinesin motor domain

Ligands and Environments

6 bound ligands:
Ligand ADP 2 x ADP
Ligand MG 2 x MG
Ligand EDO 8 x EDO
Ligand MES 1 x MES
Ligand GOL 1 x GOL
Ligand NO3 1 x NO3
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P21
Unit cell:
a: 51.654Å b: 78.254Å c: 93.467Å
α: 90° β: 94.511° γ: 90°
R-values:
R R work R free
0.216 0.214 0.26
Expression system: Escherichia coli BL21(DE3)

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